Oncology Applications of Epigenetics in Healthcare Offering Treatment to Cancer

Epigenetics is the study of the functions of the genes affected by varying behaviors and environments without modifying the DNA sequence. Gene expression can be defined as when and how often proteins are developed within the genes. Epigenetic changes affect gene expression to make them off or on, while genetic changes take place. The environmental behaviors, including diet and exercise, cause epigenetic changes. It is easier to experience the connection between genes, behaviors, and the environment. 

Epigenetics contributed $1,563.8 million in revenue in 2021, and it is expected to reach $6,460.5 million in 2030, progressing at a 17.1% growth rate. The epigenetic changes are reversible and take place throughout life. The epigenetics at the time of birth varies from the epigenetics during childhood or at old age. 

Epigenetic changes can affect gene expression in various ways. It includes:

DNA Methylation: DNA methylation functions with the addition of a chemical group to DNA, this chemical is added at specific places on the DNA that further blocks the proteins attached to DNA for identifying the gene. Demethylation can result in the removal of this chemical from the DNA. Usually, methylation inactivates genes, and demethylation activates them.

Histone Modification: Histones can be defined as the DNA wraps around the proteins, and proteins cannot access these DNA wraps. Several genes wrapped around histones are inactive, while several which are not wrapped are active. Chemical groups can be removed or added to histones and change if a gene is wrapped or unwrapped.

Non-coding RNA: DNA gives coding instructions and non-coding of RNA; proteins are created by utilizing RNA coding. Non-coding RNA provides support in controlling gene expression by attaching coding RNA and several other proteins, that further breaks down the coding RNA to stop it from further creating proteins. Moreover, non-coding RNA also utilizes proteins to change histones and turn genes off or on.

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Why Telecom Industry Dominates Optical Spectrum Analyzer Market?

 The power distribution of an optical source across a certain wavelength range is measured and shown by a precise device called an optical spectrum analyzer. In 2021, the optical spectrum analyzer market accounted for $326.6 million, which is predicted to hit a $588.8 million value by 2030, advancing at a 6.8% CAGR from 2021 to 2030. The rise is mostly attributed to changes in the healthcare, consumer electronics, and telecommunications industries as well as the growing demand for these analyzers.

Applications for the OSA are many in the IT & telecommunications, healthcare & medical, and other industries. To fulfill the need for optical spectrum analyzers, it is therefore expected that tailoring the product to a specific application will be a wise strategic choice. As a result of the enormous increase in internet customers, both residentially and commercially, operators were obliged to increase their capacity. This encouraged the operators to spend money on testing tools like analyzers.

Optical Spectrum Analyzer Market Segmentation Analysis Report

It is predicted that users of mobile devices, as well as other cloud-connected devices, would substantially increase their data consumption, which will be accommodated by the development of 5G network technology. Since technology has advanced over the past few years, it has been possible to use the millimeter wave frequency spectrum extensively to overcome the difficulties associated with a lower frequency and high-speed communications. 

Additionally, there is a growing demand for cost-effective 5G systems with a high dynamic range and cutting-edge capabilities to enhance the quality of connections in emerging nations of the Asian, African, and LATAM regions. Thus, as 5G technology advances, there is an increasing need for analyzers in emerging regions. Additionally, the global optical spectrum analyzer market will increase over the next few years due to a rise in infrastructure development and sophisticated networks throughout the globe.

Based on end use, the optical spectrum analyzer market in the healthcare market is predicted to increase at a pace of roughly 8% during the projected period. This is a result of the sector's expanding production and R&D of short-wavelength lasers, consumer products, material processing systems, and passive devices.

The healthcare industry has made significant strides over the past several decades as a result of increased government support for research and funding projects. Currently, fiber optics are often used in healthcare and medical applications, including lab-on-a-chip and patient-centered medicine, where endoscopy is gaining significant momentum. This will increase the use of OSAs in R&D and the production of medical equipment.

The optical spectrum analyzer market's highest revenue share belongs to the telecoms industry. The usage of optical spectrum analyzers in the telecom sector is being boosted by the fast-changing telecom environment, the rising uptake of 5G communications, and the booming R&D of future more advanced telecom networks. Additionally, OSAs are very important to producers of telecom equipment because of the diverse variety of uses they have in the sector, namely in R&D and field uses. 

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Growing Sale of EVs Influences Lithium-Ion Battery Metals Market

 A lithium-ion battery is a particular kind of rechargeable battery made up of cells where lithium ions travel during discharge from the negative electrode via an electrolyte to the positively charged electrode and back again during charging. Li-ion batteries commonly employ graphite for the negative electrode and an intercalated lithium material for the positive electrode. The global lithium-ion battery metals market is predicted to touch $192,610.3 million by 2030.

Lithium-ion Battery Metals Market Revenue Estimation and Growth Forecast Report

The lithium-ion battery metals market's largest revenue contributor is the automotive sector. The fundamental reason for this is that the biggest emerging and developed economies are placing more and more emphasis on reducing carbon emissions and moving to electric vehicles. In 2021 set a record for this philosophy with 6.6 million electric vehicle sales, or 9% of the worldwide car market. This is causing the demand for the metals used in automobile lithium-ion batteries to increase, particularly those used in electric vehicles.  

Read Full Report: Lithium-ion Battery Metals Market Revenue Estimation and Growth Forecast Report

China is the market leader in the EV sector as a result of the government's strict pollution rules and the incentives it is providing to create a favorable EV environment, including for the purchase of vehicles. Additionally, the nation leads the EV market because of its emphasis on a robust battery production sector and extensive accessibility of the charging infrastructure.

Additionally, as part of their efforts to diversify their economies, regional governments are making large investments in the ICT industry, which will boost consumer demand for electronics in the upcoming years. Because these devices run on lithium-ion batteries, the rising demand for them will increase the need for an effective power supply. According to research, the U.S. holds a 36% share of the global ICT market, while the China and EU each hold a share of about 11%.

The lithium-iron phosphate cell chemistry would have the largest CAGR, at 34.1% in the lithium-ion battery metals market. This is due to the LFP chemistry's superior energy density, capacity, and cost-effectiveness versus others. In essence, it is expected that the booming demand for LFP batteries from the automotive and energy storage industries would support the category's leading position in the coming years.

The LFP substance is also less harmful to the environment. Manufacturers have recently dramatically boosted the number of R&D projects they are working on to create LFP batteries and the capacity to make the cells, which has contributed to the expansion of the lithium-ion battery metals market.

Currently, CATL is the leading manufacturer of LFP batteries, which Tesla uses in its Shanghai-made short- and medium-range electric vehicles. CATL also sells these batteries to Europe. Many other LFP battery market participants have been increasing their R&D expenditures and portfolio-enhancing funding like this.

With a 33.8% CAGR, the APAC lithium-ion battery metals market, which presently uses the most lithium-ion battery metals, will have the second-fastest increase throughout the projected period. The growing demand for EVs is the main factor driving the need for the metals required to create Li-ion batteries. The requirement for cathode and anode materials for automotive Li-ion batteries is still on the rise in the area as EVs are being embraced at a rapid rate in Japan, South Korea, Australia, and India.  

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AI-Based Medical Imaging Market To Reach Above $11,921 Million by 2030

In 2021, size of the AI-based medical imaging market was around $1,093 million and will reach above $11,921 million by 2030, propelling at a mammoth CAGR of above 30% in the years to come. The main factors pushing the industry are the increasing occurrence of chronic illnesses, snowballing requirements for medical services for the elderly population, and increasing R&D expenditure in the healthcare industry.

CT had the largest demand of 30%, in 2021, and will continue to lead also in the years to come. This is because of the rising occurrence of many chronic diseases like cancer and CVD conditions, and the snowballing requirement for AI-integrated innovative imaging solutions. 

Furthermore, the industry growth is also propelled by the momentous investment precisely for the expansion of AI-enabled solutions, the enormous population suffering from cancer and further chronic diseases, and numerous small, and large companies that offer a wide variety of AI-based CT imaging solutions.

Hospitals had the largest demand for these diagnostic solutions in 2021, and they will advance with a growth rate of 30% in the years to come. This is credited to the omnipresence, easy availability, and preference of hospitals as compared to other medical facilities. Furthermore, reimbursement plans are among the main factors behind the industrial dominance of hospitals.

The growing awareness of the benefits of AI techniques and their broad application areas has resulted in the high implementation of AI in the medical diagnostic sector. Several companies are teaming up or collaborating for offering the most prominent technologies to consumers in healthcare. These AI-based medical technologies help medics in their decision-regarding analysis and treatment. Therefore, doctors adopt these lucrative, accurate, and safe solutions as compared to the traditional ones, which, in line, help the industry to grow.

APAC will witness the highest growth in the near future, proceeding with a striking growth rate of more than 30%. This exponential growth is because of the aging population, a surging requirement for healthcare services, and snowballing investments by numerous private and government companies.

 There has been an increasing development of the healthcare sector, and because of this, the demand for AI-based medical imaging solutions is on the rise.

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Rising Usage of the Digital Biomarkers for Effective Disease Management

Digital transformation in various industries has paced up operations with increased efficiency and revenue generation. A digital biomarker is such innovative technology in the healthcare sector. 

The digital biomarkers industry generates $1,850 million revenue in 2021, and it is projected to capture $21,986.2 million revenue in 2030, advancing at a rate of 31.6%. The rising prevalence of chronic diseases and technological advancements in digital healthcare systems drive the industry.

Digital biomarkers are the foundation for precision medicine as they provide strong evidence of patient outcomes. Moreover, the advancing healthcare system to deliver a value-based paradigm leads to the rising adoption of innovative solutions such as digital biomarkers. The major goal to attain such technological advancements is to enhance tailored care delivery for a better analysis of the healthcare information of the patients.

The data collection tool holds a significant share of the digital biomarkers industry accounting for 90%. These tools support data gathering and novel digital biomarkers extraction that are more precise, patient-centric, and clinically useful.

Under the data collection category, wearables which include smartwatches and fitness bands, hold a significant share of the digital biomarkers industry. Wearables by major brands such as ActiGraph, Garmin, Fitbit, and other others have proved successful in clinical studies in various fields of medicine. It includes cardiovascular diseases, rehabilitation, mental health, diabetes, and oncology for assessing the heart rate, sleep-related outcomes, sweating intensity, blood oxygen level, and step count.

Moreover, digital biomarkers can enable longitudinal insights into diseases that have progressed over time. Such novel insights cannot be tracked by current diagnostic tests for diseases such as Alzheimer’s disease, depression, and dementia. Furthermore, the rising engagement of patients has facilitated them to track their health and set their own goals for improved medication adherence and disease handling led by lifestyle interventions.

Wearable devices are increasingly being used for developing highly personalized and adaptable treatment plans. It allows prompt therapeutic intervention implementation based on minor changes in the health patterns.

The cardiovascular application of digital biomarkers contributes an extensive share to the industry revenue, accounting for 20%. It is led by the growing prevalence of cardiovascular disorders, which causes 32% of the global mortality, with an estimated death of 17.9 million people each year, according to a government source.

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What Use Are Data Loggers for Global Automotive Industry?

With more than 1.3 million people dying in road accidents each year, as per the World Health Organization (WHO), the focus on making roads safer is strengthening. Since most of the accidents are attributed to human error, many governments are mandating the adoption of some level of vehicle autonomy so that the burden on the driver can be reduced. Such awareness and the increasing inclination of people for improved vehicles are leading to the integration of advanced driver assistant systems (ADAS), which automate many functions of automobiles and display real-time information.

As per P&S Intelligence, this will be a key reason behind the growth of the automotive data logger market during 2020–2030, since valuing around $3 billion in 2020. This device is similar to the all-important flight data recorder (FDR) in airplanes, which records what happens to the aircraft systems with every push of the button or foot-operated pedal, shift of the stick, push or pull of the lever, and turn of the control knob. 

In the automotive sector, data loggers are used to track and monitor the functioning of not only the mechanical systems, such as engines, wheels, brakes, and steering, but also of the electronic systems, such as ADAS. This information is used by automakers to make future systems better or send alerts to vehicle owners regarding maintenance, servicing, or replacement. Further, automakers also use these instruments before the vehicles come out of the factory, during the testing phase. With the stringent emission control and passenger safety mandates, rigorous vehicle testing has become indispensable.

As a result, North America is the largest automotive data logger market, as several U.S. states and Canadian provinces have already tweaked their transportation regulations to accommodate autonomous vehicles. Moreover, in 2015, the National Highway Traffic Safety Administration of the U.S. made the installation of such devices necessary in trucks, so that driving hours could be recorded electronically. Driver fatigue is the key reason behind accidents involving trucks in the country, which is why electronic logging devices are now being used to ascertain how long trucks are being driven.

In the coming years, the incorporation of these devices will pick up the fastest in Asia-Pacific (APAC), which accounts for the highest automotive production and sales in the world. In addition, with the increasing disposable income of people here and them becoming rapidly tech-savvy, the demand for cutting-edge automotive features is increasing. Moreover, with the presence of a large number of electronics companies in the region, such devices are available at cost-effective rates.

Hence, with the increasing focus on enhancing road safety, the procurement of data loggers by automakers, fleet operators, and government agencies will boom.

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Acoustic Vehicle Alerting Systems Enhancing Pedestrian Safety

The International Energy Agency (IEA) forecasts that the global stock of plug-in hybrid electric vehicles (PHEV) (trucks) and battery electric vehicles (BEV) (trucks) will rise from 228 units in 2020 to 900,264 units by 2030 and 30,872 units in 2020 to 860,942 units by 2030, respectively. The IEA also predicts that the global PHEV (cars) and BEV (cars) stock would surge from 3,346,713 units in 2020 to 44,355,904 units by 2030 and 6,850,327 units in 2020 to 79,975,992 units by 2030, respectively. The rising electric vehicle (EV) sales is fueling the requirement for acoustic vehicle alerting systems (AVAS).

Moreover, the declining cost of automobile components, such as speakers, amplifiers, copper coils, and battery backs, will help the acoustic vehicle alerting system market display a healthy value CAGR of 11.9% during 2020–2030. According to P&S Intelligence, 24.7 million AVAS were installed in electric two-wheelers and passenger cars in 2019. The market is expected to generate $10,578.8 million revenue by 2030. AVAS has become an integral part of EVs because it concerns pedestrian safety, especially of the more-vulnerable sections, such as aged people, children, blind people, and individuals with partial vision.

Similarly, in July 2019, sound experts of Daimler AG designed an identifiable note for Mercedes EVs at its acoustic test facility at the Mercedes-Benz Technology Centre in Sindelfingen, Germany. This note has been created in adherence to the European Union (EU) directive that propounds that any new EV in Europe must feature an acoustic warning up to a speed of 20 km/h. Other companies working toward the creation of advanced AVAS components are Mando Corporation, Honda Motor Co. Ltd., Renault–Nissan–Mitsubishi Alliance, Robert Bosch GmbH, Volkswagen AG, and DENSO CORPORATION.

Whereas, Europe is expected to adopt AVAS components at the highest rate in the foreseeable future owing to the burgeoning EV and hybrid vehicle sales and increasing implementation of government regulations that mandate the inclusion of such components. For instance, the EU plans to phase out ICE-driven vehicles to mitigate greenhouse gas emissions and reduce oil imports. Many European nations aim to ban ICE-powered automobile sales between 2030 and 2040.

Therefore, the booming EV sales and plunging automobile component prices will fuel the adoption of AVAS globally.

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