Two of the biggest causes of death worldwide are cardiovascular diseases (CVDs) and cancer, which carry an annual mortality of 17.9 million and 9.6 million, respectively, according to the World Health Organization (WHO). Other common chronic diseases are chronic obstructive pulmonary disease, which affects more than 250 million, and diabetes, from which at least 422 million suffer each year. This high case count, which is rising every year, is propelling research and development (R&D) activities in the fields of diagnosis and treatment.
Browse report overview and detailed TOC on Label-Free Detection Technology Market Industry Analysis and Growth
As per P&S Intelligence, the growing chronic disease incidence will drive the label-free detection technology market from $1,197.5 million in 2019 to $3,097.4 million by 2030, at a 9.0% CAGR between 2020 and 2030. During drug discovery, the tissue or cell on which the effect of an investigational drug is to be tested is attached to a label, or tag, which helps in detecting the activity of the drug on it. The label-free detection technology eliminates the requirement for labeling, instead, using the size, molecular weight, electrical impedance, charge, refractive index, and dielectric permittivity of the drug in the tissue.
For all such purposes, a range of technologies are used, such as surface plasmon resonance (SPR), mass spectrometry, microplates/reader-based technology, bio-layer interferometry (BLI), and calorimetry. Among these, mass spectrometry is used the most widely, on account of its preference among researchers to ascertain the structural characteristics of the bound proteins and derive information about molecules. In the coming years, the usage of SPR will rise rapidly, as it is cost-effective and reproducible, requires minimal sample volumes, and uses a continuous flow mechanism.
Hence, as the demand for novel drugs to combat chronic diseases and keep the mortality count low increases, so will the requirement for the instruments and consumables used for label-free detection.
