What are Major Factors Fuelling Surge of Global Organ-On-Chip Market?

 One of the biggest factors propelling the demand for organ-on-chip is the increasing number of investments being made in research by the governments of several countries all around the world.  For instance, the National Center for Advancing Translational Sciences (NCATS) gave a research grant worth $2 million to Emulate Inc. in July 2017, in order to allow the company to leverage its human Brain-Chip system and create a fully automated research platform for conducting experiments on the International Space Station.

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The other major factor responsible for the rising demand for organ-on-chip is the increasing need for alternatives to the conventionally used animal models in research activities. In many countries, doctors and medical researchers are raising concerns over the scientific validity and translatability of the animal alternatives of human diseases and this is massively boosting the demand for alternative drug and diseases research techniques. The increasing initiatives being taken by the pharmaceutical companies for promoting the adoption of organ-on-chip models are expected to further push the demand for organ-on-chip based research methods in future.

Driven by the above-mentioned factors, the global organ-on-chip market is predicted to advance at a 40.1% CAGR during 2018–2025 (forecast period). The valuation of the market is expected to rise from $11.0 million in 2017 to $163.1 million by 2025. Organs-on-chips are essentially tiny models of body parts, which can simulate the functioning of the real thing. These products are used in various applications, such as physiological model development, toxicology research, and drug discovery. Amongst these, the drug discovery applications are expected to record the fastest growth in the usage of organ-on-chip products during the forecast period.

Hence, it can be concluded that owing to the surging investments in advanced technologies and research methods in the healthcare industry and the shifting focus toward alternative testing models in drug discovery and disease research processes, the demand for organ-on-chips will increase considerably in the coming years.

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Rising Government Support Aiding the Organ-on-Chip Market to Grow

The increasing need for animal alternatives in medical research and growing government funds and grants for studies are the prime factors strengthening the organ-on-chip market, globally. In 2017, the market generated a revenue of $11.0 million, and it is predicted to witness a 40.1% CAGR during the forecast period (2018–2025). Organ-on-chip is a 3D microfluidic cell culture chip, developed to simulate the mechanical and natural physiological forces that cells are subject to inside the human body. These chips are integrated with living human cells as well as tiny fluidic channels to propagate air and blood flow.   

Based on type, the organ-on-chip market is broadly classified into liver, heart, lung, kidney, and intestine-on-chip. Among these, in 2017, the liver-on-chip classification dominated the market in terms of revenue, and it is expected to exhibit the fastest growth with more than 45.0% CAGR during the 2018–2025 period. The surging incidents of chronic liver disease and rising research and development activities for therapeutic interventions are the major factors responsible for the growth of this classification.

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The increasing collaboration among the key players and rising number of product launches are helping in the development of the organ-on-chip market. For instance, in October 2017, Charles River Laboratories International Inc. (Charles River) permitted InSphero AG to license its patient-derived xenograft (PDX) tumors. Furthermore, the company was to use the proprietary 3D cell culture technology of InSphero to further complement and expand its pre-clinical services, utilizing the in-vitro 3D InSight Tumor Microtissues obtained from its current PDX tumors.

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Thus, the growing need for alternative models for medical research studies is expected to boost the organ-on-chip market progress during the forecast period. Further, the increasing government funding is helping the market players conduct more research activities. Government agencies such as the National Institutes of Health offers grants to facilitate the research programs. For instance, in July 2017, Emulate Inc. declared it had been granted an undisclosed amount to utilize its human Brain-Chip system to create a fully automated research platform for carrying out experiments on the International Space Station.

Hence, the rising demand for alternative models for medical research and growing government support are accelerating the market growth.

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