Showing posts with label Protein A Resin Market. Show all posts
Showing posts with label Protein A Resin Market. Show all posts

Surging R&D Activities in Protein Research Propelling Demand for Protein A Resins

 The surging investments being made in protein-based research and development (R&D) activities are causing a sharp surge in the demand for protein a resins across the world. Many private and public organizations are making huge investments in protein-based research programs for improving therapeutic approaches. For example, the National Institute of Health (NIH), which is a medical research center located in the U.S., invests around $32.3 million in medical research every year.

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As per the United Nations Population Fund, people in the age bracket- 60 years or above account for as much as 12.3% of the total population of the world. Moreover, this share is predicted to rise to nearly 22% by 2050. The rising incidence of chronic diseases is also augmenting the requirement for novel therapeutic processes for better and more effective disease management. The growing demand for novel therapeutic procedures is propelling the worldwide requirement for protein a resins. 

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Between these, the demand for the recombinant source was found to be higher during the past few years. This was because of the high requirement for protein a resins in antibody purification processes. Antibody purification and immunoprecipitation are the major application areas of protein a resins. Of these, the usage of protein a resins will rise enormously in antibody purification processes in the coming years, on account of the growing requirement for antibodies, especially monoclonal antibody for various therapeutic purposes.

Geographically, the protein a resin market is predicted to register the fastest growth in the Asia-Pacific (APAC) region in the forthcoming years. This will be a result of the mushrooming usage of protein a resins for drug discovery, rapid technological advancements, and the increasing number of research and development activities being conducted in the life sciences domain in this region. In APAC, the usage of protein a resins was observed to be the highest in Japan in the past.


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How are Increasing Research Activities Driving Protein A Resin Market?

The research activities, particularly protein research, in several therapeutic areas are rising in order to address the unmet medical requirements. Before, the development of proteins and monoclonal antibodies as therapeutic agents was avoided by pharmaceutical companies because of their low stability, size, rate of degradation, and poor delivery. However, now monoclonal antibodies and proteins are being developed for catering to the unmet needs in different therapeutic areas, such as oncology, infectious diseases, metabolic diseases, and cardiovascular diseases. This has resulted in increased attention on making use of proteins which mimic the function of mediators involved in different pathologic processes. Attributed to this, the demand for protein A resin is rising.

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Protein A resin is an affinity chromatography resin which is utilized as a separation medium during purification techniques of immunoprecipitation and chromatography. As per a P&S Intelligence report in 2019, the global protein A resin market size reached a value of $486.4 million and is expected to generate a revenue of $1,020.7 million by 2030, advancing at a 7.0% CAGR during the forecast period (2019–2030). Two end users of protein A resin are academic institutes & research laboratories and biotechnology & pharmaceutical industries. Out of these, biotechnology & pharmaceutical industries are projected to make the most use of protein A resin during the forecast period.

The two major applications of protein A resin are immunoprecipitation and antibody purification. Between these two, the larger demand for protein A resin was created for the antibody purification application during 2014–2019, and the resin is further predicted to be the more in demand for this application during the forecast period. This is because of the high production and rising demand for antibodies primarily monoclonal antibody for therapeutic application. Geographically, North America is expected to create the largest demand for protein A resin during the forecast period, owing to the presence of large-scale manufacturers of drugs.

A major driving factor of the protein A resin market is the growing burden of chronic diseases. For example, as per the International Agency for Research on Cancer, a specialized cancer agency of the World Health Organization, 12.7 million new patients were diagnosed with cancer in 2008 and the number is predicted to reach 21.4 million by 2030. Monoclonal antibodies hold multiple properties as therapeutics, including suitable pharmacokinetic profiles, low toxicity and immunogenicity, and customizable solubility features. Due to this, pharmaceutical and biotechnology companies are focusing on developing novel therapeutics for the treatment of these diseases.

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