Sepsis comes to the forefront with a response to an infection. From time to time, chemicals released by the immune system in the blood for fighting an infection can trigger a chain reaction of irritation all over the body. This is sepsis, and it can lead to organ failure or even death.
Any infection can be a cause of sepsis, but some are more prone to cause sepsis than others. These include, urinary, respiratory, gastrointestinal, and skin infections. In the respiratory tract, SARS-CoV-2 are prevalent causes of sepsis.
The Complications and Cost of Sepsis
Sepsis can take a toll in terms of people impacted, costs to the healthcare system, and lives lost. Sepsis is a prime reason for deaths of children in the U.S., overtaking pediatric cancers. Worldwide, 3.4 million children expire because of sepsis every year, including 6,800 children from severe sepsis. More adults in the country die as a result of sepsis than from breast cancer, prostate cancer, and overdoses of opioid combined.
Even patients getting over sepsis can have lasting and life-altering health influences. Actually, 50% of sepsis patients have with long-term psychological and physical impacts.
Antimicrobial Resistance and Problem of Sepsis
Time is key when concerned with sepsis. Early diagnosis of sepsis and quick introduction of antimicrobial therapy is correlated with upgraded results for patients. That urgent requirement for beginning therapy can prompt providers for administering broad-spectrum antimicrobials well before receiving the lab results enabling more targeted treatment.
Unfortunately, this reflexive usage of broad-spectrum antimicrobials can deepen the more and more serious problem of antimicrobial resistance. It’s a circular issue, the broad-spectrum antimicrobials used for treating sepsis can lead to better antimicrobial resistance. And pathogens becoming resistant can cause sepsis when an infection can’t be controlled.
A key to disrupting this pattern is fast identification of the causative pathogen, which is targeted, instead of empiric broad-spectrum, therapy.
It is because of the promulgating cases of hospital acquired infections and sepsis, the demand for sepsis diagnosis around the world.
