Increasing Incidences of Organ Failure Leads to Rising Demand for Transplantation

Transplantation in healthcare helps in saving the lives of numerous people whose organs, or cells have stopped functioning. When no other alternative works, human cells, tissues, or organs are transplanted.

Transplantation can be defined as tissue, organ, or cell group removal from donor to recipient, or positioning from one site to another in the same person. In 2021, the transplantation industry contributes $13,605.9 million, and it is projected to advance at a rate of 9.2% and capture $30,117.5 million in 2030.

Transplantation is not a simple healthcare procedure in medicine. It involves numerous complications, as the transplantation of organs or tissues from one person to another, may cause rejection from the recipient’s immune system, which may destroy the donated organ or tissue, to prevent such immune response medication is required. Under such conditions, treatment may vary depending on the organ and tissue being transplanted, compatibility level between recipient and donor, and various other factors.

 Some of the major transplantation in healthcare

 

• Patients suffering from corneal blindness can get their eyesight back with corneal grafting
• Hematopoietic stem cell transplantation can help in curing congenital diseases along with leukemia.
• Recipient patients of human heart valve transplantation do not require to undergo long-term anti-coagulation therapy, done under the best replacement situation.
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Xenotransplantation: Living cells, organs, or tissues of animals or humans, along with cells, body fluids, tissues, or organs ex vivo with xenogeneic materials being alive, are capable of constituting an alternative to human origin material, and fulfill the requirement for human material for transplantation.

 Tissue Transplantation in the Same Person

The most prevalent transplantation is tissue transplantation, in which one tissue from one part of the body is transplanted to another part through autograft, the process is known as autotransplantation.

 Several types of autografts:

 Skin Graft: It involves the usage of healthy skin to support the healing of the wound or burn on another body part.

 Blood Vessel Graft: It helps in providing an alternative passage for blood flow to bypass a blocked artery, such as heart bypass surgery.

 Bone Graft: Bone grafting helps in reconstructing the damaged area of the body, such as in spinal fusion.

 Bone Marrow Graft: For instance, bone marrow needs to be collected in cancer patients before, they undergo chemotherapy. As, after high-dose of chemotherapy results in the replacement of blood stem cells.

The increasing incidences of chronic diseases, such as solid tumors, myelodysplastic disorders, plasma cell disorders, immune system disorders, and kidney failures, are leading to the growing prevalence of transplantation.

Increasing awareness of organ donations, technological advancements such as kidney transplantation with robot assistance, and rising success rates in organ transplantation, increase people’s confidence to undergo organ transplantation.

The rising elderly population increases the demand for orthobiologics for reducing pain, fast tissue healing, and restoration of normal functioning. Numerous, startup companies are receiving investments to expand their operations. For example, a shoulder replacement manufacturer, Catalyst OrthoScience raised $12.3 million in the financing round and utilized it to launch Archer 3D Targeting Imaging Software and Archer R1 Reverse Shoulder System.

Therefore, the rising elderly population increases the prevalence of transplantation, with growing incidences of organ failure, or chronic diseases.

 Read More Transplantation Market Scope and Size

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How Does Prevalence of the Chronic Diseases Fuels Growth of the Transplantation Industry?

The transplantation market generates $13,605.9 million revenue, and it is projected to capture $30,117.5 million revenue in 2030, growing at a rate of 9.2% from 2021 to 2030. It is led by the rising incidences of chronic diseases, such as solid tumors, kidney failure, myelodysplastic disorders, plasma cell disorders, along with disorders of the immune system. 

Moreover, immunosuppressive drugs are projected to experience the fastest growth, rising at a rate of 9.6% in the coming future. It is attributed to the growing prevalence of autoimmune disorders, such as multiple sclerosis, alopecia areata, and arthritis, along with the growing incidences of organ failures, more specifically kidney, liver, heart, and lungs. The rising disposable income of the population in emerging nations is also projected to boost the demand for immunosuppressive drugs in the coming future. 

Under the end user segment, hospitals contribute 50% revenue share to the industry, emerging as major centers for tissue and organ transplantation. In addition, the rising advancements in the healthcare infrastructure, along with the presence of a well-defined database of donors and patients requiring transplants fuel the revenue of the hospitals. 

Transplantation centers contribute extensive revenue to the industry, and it is projected to retain their position in the coming years, led by the growing awareness among donors and patients about these centers due to specialty surgeons and staff members for performing procedures. Moreover, the R&D activities performed in these centers, result in advanced transplantation procedures. 

North America captures the 40% share of the transplantation industry. The U.S. leads the region’s industry, led by the massive number of patients requiring organ transplantation for treatment, more specifically for kidneys, liver, pancreas, heart, liver, and lung transplantation. In addition, growing R&D in healthcare increases the success rate of such activities. 

Therefore, the rising prevalence of chronic diseases boosts industry growth, with growing requirements for organ transplantation.

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