How is growing R&D investments in Drug Discovery and Development Driving Synthetic Biology Market?

The need for advanced and innovative drug discovery and development has increased considerably as the prevalence of various diseases, such as neurological disorders, immunological disorders, infectious diseases, and cancer is rising. Due to this, several biopharmaceutical and pharmaceutical companies are becoming more inclined toward the development of new and more effective biopharmaceutical drugs. This in turn, has been made possible because of the growing research and development investments in drug discovery and development. Since synthetic biology provides innovative solutions for drug discovery, its demand is surging as well. Using synthetic biology, living organisms are genetically developed for required functions in research laboratories. The field derives input from molecular and cell biology, biochemistry, bioinformatics, mathematics, and evolutionary systematics. Synthetic biology elucidates disease mechanisms and target identification, along with providing avenues to design and discover novel biopharmaceuticals and small chemotherapeutic molecules.

According to a research conducted by the P&S Intelligence, the global synthetic biology market is expected to generate a revenue of $23.8 billion and advance at a CAGR of 35.4% in the near future. Among several reasons for the growth of this market is the increasing geriatric population. According to the United Nations Department of Economic and Social Affairs, the population of people aged 60 years and above is rising at a high rate; the number rose from 9.2% in 1990 to 11.7% in 2013 and is further predicted to reach 21.1% by 2050. People aged 60 years and above are more prone to illness because of low immunity and metabolic rate, due to which diseases such as cancer and immunological diseases affect elderly people more severely. The treatment of such diseases requires more effective biotherapeutics and synthetic biology helps achieve the same by enabling designing of novel strategies for the treatment as well as production of cheap drugs.


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The segments of the field of synthetic biology are technology and tool. Among these, synthetic biology technology was the most in demand during 2011–2014. Synthetic biology has become more significant due to the utilization of several innovative and advanced technologies which are used in the field of life sciences for developing biological systems and bio-based products, designing, and redesigning. The two foundational technologies applied by synthetic biology are DNA synthesis and DNA sequencing. DNA synthesis provides the ability to design new, synthetic biological systems and parts and DNA sequencing helps understand the components of natural biological systems. Synthetic biology technology is further bifurcated into enabling and enabled.

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Geographically, North America dominated the global market, among all the regions in 2014; and it is expected to grow with a CAGR of 35.2% during the period 2015 – 2020. However, the Asian market is expected to witness fastest growth, with a CAGR of 39.8% during the forecast period.

The key companies operating in the global synthetic biology market include E. I. du PONT de Nemours and Company, Amyris Inc., GenScript USA Inc., Intrexon Corporation, Thermo Fisher Scientific Inc., Synthetic Genomics Inc., Royal DSM, Novozymes A/S, New England Biolabs Inc., and Integrated DNA Technologies Inc.
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US Electric Bus Market is Fastest Growing and Demanding with CAGR of 23.9% during 2019–2024

The U.S. electric bus market generated revenue worth $445.7 million in 2018 and is projected to register a CAGR of 23.9% during 2019–2024. Among vehicles, hybrid electric vehicles held the largest share in the market during the historical period.

Advanced hybrid electric buses are currently being deployed by many transit agencies in the U.S. Moreover, public and private investments over the last two decades have facilitated development of the technology used in these buses to the point where it has become viable and competitive with respect to an internal combustion engine (ICE). This has supported the dominance of this category in the US electric bus market.

Growing preference for depot charge buses is the key trend observed in the U.S. electric bus market. Battery electric buses are currently offered in two models. One is a short-range bus that uses small on-board batteries for traction, which are charged en route. The other is an extended-range bus that is equipped with larger on-board batteries, which undergo slow overnight charging. In the past, the majority of the buses procured in the country were on-route charge buses; however, recent procurement orders have majorly been for depot charge buses. This is due to the similar operational characteristics of these buses as those of conventional diesel buses. Furthermore, with improving battery technology, the range of depot charge buses is improving, enabling longer route coverage.



Segmentation Analysis of U.S. Electric Bus Market
  • Battery electric buses are registering faster growth in demand across the country, primarily due to the support of federal and state governments (in form of subsidies and grants) for the adoption of zero-emission buses. Furthermore, plug-in hybrids may not play any significant role in the near future in the U.S. electric bus market, mainly due to their manufacturing complexity, high cost, and tailpipe emissions.
  • Electric buses with length more than 40 feet are expected to remain the larger category in the market during 2019–2024. This is primarily due to the difference in fuel mileage in diesel hybrid and diesel buses, which favors hybrid technology for longer articulated buses.
  • Electric buses that run on lithium-ion batteries are gaining popularity and witnessing considerable growth in demand in the U.S. electric bus market. Lithium-ion batteries are safer than other batteries in the market and are, therefore, more preferred for large-sized electric buses. Furthermore, falling prices of these batteries, coupled with their advantages such as lower maintenance cost, smaller size, lighter weight, higher energy density, and lower self-discharge over nickel–metal hydride batteries, are supporting the market growth in this category.
  • During the forecast period, inductive charging is expected to be the fastest-growing category in the U.S. electric bus market, as it facilitates faster charging, thus reducing the range anxiety of operators. Owning to this factor, several charging system manufacturers are collaborating with electric bus makers and public transit authorities to boost the adoption of these systems in the country.
Competitive Landscape of U.S. Electric Bus Market
The U.S. electric bus market is currently in its nascent phase, with the presence of few key manufacturers. Some of the major battery electric bus manufacturers in the country are Proterra Inc., BYD Motors Inc., and NFI Group Inc. Furthermore, key hybrid electric bus manufacturers in the market are GILLIG LLC and NFI Group Inc.

In April 2019, Allison Transmission Inc. unveiled new ABE series, the first e-axle advanced ultra-low floor electric bus powertrain system at the Advanced Clean Advanced Clean Transportation Expo. Furthermore, in December 2018, NFI Group Inc. announced that it was awarded a contract for seven 40-foot battery electric Xcelsior Charge heavy-duty transit buses by the Victor Valley Transit Authority (VVTA).

Some other notable players operating in the U.S. electric bus market are Blue Bird Corporation, GreenPower Motor Company Inc., COBUS Industries GmbH, ElDorado National California Inc. and Nova Bus Corporation.

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CNG and LPG Vehicle Market Growing due to Strict Emission Norms


The compressed natural gas (CNG) and liquefied petroleum gas (LPG) vehicle market is being driven by government initiatives for their adoption, low operational costs of such vehicles, and strict emission control norms across the world. In 2015, 45,952.4 thousand units of such vehicles were sold, and the sales are projected to grow at a 10.1% CAGR during the forecast period (2016–2022) to ultimately number 88,947.1 thousand. As such vehicles produce less emissions compared to gasoline (petrol) alternatives, these are predicted to witness increasing popularity and adoption.

When segmented by vehicle type, the market is categorized into passenger car, bus, and light & heavy-duty truck. During the historical period (2012–2015), passenger cars dominated the LPG and CNG vehicle market in terms of the total units sold. The reason behind this was the strict emission norms in North America and Europe that are helping curb gasoline vehicle sales and promoting clean-fuel vehicle adoption. The U.S. Environmental Protection Agency (EPA) had set the maximum permissible limit of carbon emissions from passenger cars for 2016 at 225 grams per miles (g/mi).



As per plans, the emissions are to come down to 143 g/mi in the country by 2025. Similarly, in Europe, during 2006–2012, the emission from cars decreased by 160 grams per kilometer (g/km), and it has to come down further to 95 g/km by 2020. Therefore, such strict regulatory framework across the world led to the high sales of LPG and CNG-powered passenger cars during the historical period. Owing to similarly stringent emission norms, light and heavy-duty trucks are expected to witness the fastest growth in the CNG and LPG vehicle market in the forecast period.

The implementation of these norms has not only compelled people to service their old vehicles to meet them, but also promoted clean energy. Governments in several countries are running campaigns to create awareness on the rising pollution levels and ways to tackle them by adoption LPG and CNG as vehicle fuels.

Apart from raising awareness, several countries are taking initiatives to promote clean fuel-driven vehicles. For instance, in Italy, people who use LPG for their vehicles get an excise tax reduction of 58 cents/liter more than that given for gasoline and 47 cents/liter more than that given for diesel. 

Another factor leading to the market growth is the adoption of clean fuel-driven buses. Though CNG and diesel buses cost almost the same, the former emit far lesser amounts of carbon. With the growing number of personal vehicles, a large number of which are still petrol or diesel fueled, the need to reduce pollution is prompting many governments to promote mass transit driven by clean fuels. For instance, in Delhi, India, all buses, whether government or private-owned, must be CNG powered.


Further, the Russian government announced plans in 2013 to increase the proportion of natural gas-fueled buses to 50.0% of the total buses in the country. As a result of such initiatives and the above-mentioned emission norms, Europe dominated the CNG and LPG vehicle market in 2015. However, Asia-Pacific is projected to grow at a massive pace during the forecast period and overtake Europe in terms of total vehicle sales by 2019.

Therefore, the need to save the atmosphere from harmful emissions will continue to raise the demand for LPG and CNG-fueled vehicles.


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How is Internet Popularity Leading Asia-Pacific Networking Equipment Market to Prosperity


In 1990, less than 1% of the global population had access to the internet, which has drastically increased to more than 47% in 2018, as per the World Bank. With the majority of the population of the world concentrated in the Asia-Pacific (APAC) region, it is home to a greater number of internet users compared to others.

Access to the internet has helped in bringing people closer by providing a smooth communication channel; however, it has also made people prone to numerous cyber-crimes. As the internet ecosystem in emerging economies is still underdeveloped as compared to developed nations, it has been found that companies in APAC are 80% more likely to be targeted by hackers.

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Physical networking devices that are used for communication and interaction between electronic devices over an established network are collectively referred to as networking equipment. The equipment helps in combining, switching, splitting, boosting, and directing the information flow over a computer network.

Therefore, to avoid such incidents in the future, governments in the APAC region are increasingly investing in cyber security by deploying various network security products, such as intrusion detection systems, firewalls, e-mail security systems, and application security systems.

According to a P&S Intelligence study, the APAC networking equipment market is predicted to reach $42,753.4 million in the near future, advancing at an 11.3% CAGR. The networking equipment comprises the following types of devices: bridges, routers, repeaters/boosters/range extenders, switches, access points, security devices, storage devices, modems, cables, and network interface cards (NIC)/ adaptors.

In the past, the highest demand was for routers due to an increasing requirement for high-speed data transmission from consumers. Routers deliver data packets to the destination network by receiving them, analyzing the internet protocol destination, and transmitting the data packets within or to another network.

APAC Networking Equipment Market Segmentation

Market Segmentation by Type
  • Router
    • By type
      • Wired
      • Wireless
    • By maximum speed
      • 150 Mbps
      • 300 Mbps
      • 450 Mbps
      • 600 Mbps
      • Above 600 Mbps
    • By end user
      • Government and transportation
      • Commercial
      • Telecom/ISP
      • Data center
      • Residential
  • Switch
    • By type
      • Managed
      • Unmanaged
    • By number of ports
      • Less than 5
      • 5–16
      • 17–24
      • 25–48
      • Above 48
    • By end user
      • Government and transportation
      • Commercial
      • Telecom/ISP
      • Data center
      • Residential
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How is Rising Need for Advanced Tires Driving European Automotive Tire Market?

In the present scenario, vehicles have a lifespan ranging between 11.1 and 12 years; the life span rose from 10.5 years in 2015 to 12 years in 2018. This has happened due to technological advancements, increasing government regulations, and growing competition between automakers. These factors have resulted in the improvement of the vehicle’s reliability and longevity over the years. This, in turn, has also led to people buying more small crossover vehicles and keeping their old vehicles longer than before, all across the world, including Europe. In addition to all this, the mileage of vehicles has increased significantly, due to which the chances of wear and tear of the tires have also risen. All these factors are driving the demand for tires in Europe.

In 2018, the European automotive tire market generated revenue of $20,037.8 million and is expected to witness a CAGR of 4.5% in the coming years. The tires for several types of vehicles are categorized into two types on the basis of design: radial and bias. The configuration of radial tires comprises overlapping steel belts under the tread and perpendicular polyester plies, which offer high integrity, ensure longer life, and facilitate smoother rides. Bias tires consist of internally crisscrossed nylon cord plies at a 30-to-45-degree angle to the tread center line, providing the tire with a rugged and tough build, in addition to increasing the sidewall puncture resistance. The demand for radial tires was more during 2014–2018 and is projected to increase significantly in the near future as well.
Due to the changing consumer preference in the European region, the need for advanced tires is increasing. The major qualities required in a tire presently are low rolling resistance for improved fuel efficiency, low wear and tear for enhanced tire durability, and better grip for increased safety quotient. In order to cater to these requirements, the automotive tire industry is witnessing the development and innovation of advanced products. For example, the speed and reliability of the tires have enhanced with the development of ultra-high-performance tires.
What are the factors impacting the growth of this market?
  1. High tire replacement rate is a major driver observed in the European automotive tire market
  2. Private labeling of tires offers ample opportunities in the European automotive tire market
High tire replacement rate has led to the growth of the European automotive tire market. Due to various technological advancements in recent years, average lifespan of vehicles has significantly increased. The average lifespan of the vehicles increased from 10.5 years in 2015 to 12 years in 2018. Factors such as growing competition among automakers and rising government regulations have led to the improvement of the vehicle’s longevity and reliability over the years.



Private labeling in the European automotive tire market offers various growth opportunities to tire manufactures. Private labeling primarily means production of tires by one company, followed by their sales under the brand of another company. Some of the tire manufacturers are involved in private labeling to meet the market demand for their products and optimize their bottom-line profits, with selling tires at high margins at high volumes. Few OEMs also maximize their production capacity by adding private labeling to their operations, which is carried out under the supervision of experts with extensive experience in manufacturing similar products. It helps them to focus on brand management, while stressing little about issues pertaining to manufacturing operations.

The field of tire manufacturing has been witnessing several advancements, such as the development of new elastomers and polymers, for overcoming the shortage and fluctuation of the prices of natural rubber. Some of the other advancements include the usage of improved grades of silica, nanotechnology, carbon black and nanocellulose, reinforced filler technology, and dual fillers.
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European automotive tire market was consolidated in nature
The European automotive tire market was consolidated with four major players, namely Compagnie Générale des Établissements Michelin, Bridgestone Europe NV/SA, The Goodyear Tire & Rubber Company, and Continental AG, together accounted for over 70% of the market share in 2018. Compagnie Générale des Établissements Michelin is the largest player in the market, due to the existence of an extensive dealer network across all European countries as well as the presence of a loyal customer base in France. The other major players operating in the market are Cooper Tire & Rubber Company, Pirelli & C. S.p.A., Yokohama Tire Corporation, Hankook Tire Company Limited, Nokian Renkaat Oyj, Apollo Tyres Limited, and Sumitomo Rubber Industries Limited.
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Advancements in Technology Augmenting Molecular Cytogenetics Market Growth


The global molecular cytogenetics market accumulated $1.8 billion revenue in 2017, and it is projected to attain a CAGR of 9.9% during the forecast period (2018–2023). The increasing popularity of pharmacogenomics in drug development and personalized disease management, advancements in cytogenetic techniques, and employment of these techniques in detecting chromosomal abnormalities are influencing the market growth. With the growing number of cytogenetic abnormalities, cases of cancer, and drugs becoming redundant in the treatment of diseases, a more robust technique is needed for determining the cause of and managing such conditions.

Molecular cytogenetics is the branch of genetics that deals with the study of chromosomal structure, its location and function within a cell, and the detection of genetic diseases. It utilizes techniques such as comparative genomic hybridization (CGH), fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and karyotyping in various applications of biology and medicine. The market is segmented by technology, application, end-user, geography, and offering. On the basis of technology, the market is subdivided into FISH, IHC, CGH, karyotyping, and others. The market for FISH is expected to grow at a CAGR of 10.1% during the forecast period.

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The CGH subdivision is further classified into standard CGH and array-based CGH, of which array-based CGH held 55.4% share in the molecular cytogenetics market in 2017. In the application segment, the market has genetic disorders, cancer, and personalized medicine as its categories. In 2017, cancer was the largest application of molecular cytogenetics, accumulating a market share of 41.9%. This is credited to the increasing prevalence of cancer and the growing focus of research groups on developing diagnostic tools for it and other genetic disorders.

The global molecular cytogenetics market is being driven by a number of factors, one being the rising cases of cancer. Cancer as a disease involves numerous mutations, which are either disease-specific or could vary from one individual to another. Molecular cytogenetics techniques such as single nucleotide polymorphism (SNP), CGH, FISH, and genomic expression profiling are not only helping researchers in identifying cancer-specific biomarkers, but are also helping doctors in providing better diagnosis, prognosis and treatment to patients.

Secondly, the advancements in molecular cytogenetic techniques have revolutionized the field of diagnostics. The automation of the cytogenetic analysis process has played a major role in the development of molecular cytogenetics by reducing manual involvement and increasing cost and time-effectiveness. Reduced manual handling of such processes has minimized the risk of errors, thus providing accurate results. It is further predicted to present the possibility of widening the range of molecular cytogenetic testing, hence increase the scope of the molecular cytogenetics market during the forecast period.

Thus, the market is set to grow during the forecast period owing to the advancements in technology in the field of biology and medicine. 
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Carsharing Market Revenue and Industry Expansion Strategies

The carsharing market generated a revenue of $5,571.2 million in 2018 and is estimated to progress at a CAGR of 11.0% during the forecast period (2019–2025), owing to advancements in technology, which are helping make the access to shared mobility services easy. The growing demand for convenient and cost-effective mobility services, coupled with government policies encouraging the use of carsharing programs, is the key factor driving the growth of the market. In simple terms, carsharing is a short–term rental service offered to customers at a certain charge.

Based on car type, the global carsharing market is categorized into luxury, executive, and economy cars. Among these, in 2018, in terms of volume, the economy category held the largest share in the market. This is attributed to the high fuel economy of these cars, which stimulates their demand for carsharing services. Furthermore, the rising gasoline prices and increasing environmental concerns are expected to push the demand for these cars across the globe in the coming years, as these cause less impact on the environment and are cost-effective.



Further, on the basis of fuel type, the global carsharing market is bifurcated into fuel-based and electric cars. Of these, in terms of volume, fuel-based cars dominated the market in the historical period (2014–2018) and are further projected to continue leading it with more than 95.0% share in 2025. However, growing initiatives toward vehicle electrification and environment protection are predicted to result in decreased gasoline usage during the forecast period. In addition, owing to low maintenance cost, electric cars are anticipated to observe increased adoption in the market for carsharing.

Carsharing services are extremely useful for the general public, especially for daily commuters, as without owning and maintaining cars, they can reach their destination. For users, these services are available day and night throughout the year, allowing them to use a car from anywhere, anytime. Besides, with the help of the carsharing company’s mobile app, commuters can directly avail the services and easily rent the car of their choice. The apps offer the necessary details and every assistance to users, so that they have a good commuting experience. Hence, mobile apps, providing easy access to cars as well as all the information related to the service, are taking the carsharing market ahead.

Introduction of mobility as a service observed as a key trend in the market

Furthermore, carsharing helps save the expenditure on owned cars, fuel, maintenance, parking, and insurance. Carsharing services require users to pay only on the basis of the time and distance the car is being driven for, along with an initial registration cost. Also, other expenses, such as those for maintenance, insurance and fuel, are borne by the carsharing service providers. Due to benefits associated with sharing services, such as cost-efficiency and easy availability, the global carsharing market is expected to grow.

Hence, with the increasing inclination of people toward convenient mobility services, the global market for carsharing is witnessing a boost.

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